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Kidney Function Research Paper

Chronic Kidney Disease Research

Chronic kidney disease is a worldwide public health problem. In the United States, there is a rising incidence and prevalence of kidney failure, with poor outcomes and high cost. There is an even higher prevalence of earlier stages of chronic kidney disease. Increasing evidence, accrued in the past decades, indicates that the adverse outcomes of chronic kidney disease, such as kidney failure, cardiovascular disease, and premature death, can be prevented or delayed. Earlier stages of chronic kidney disease can be detected through laboratory testing. Treatment of earlier stages of chronic kidney disease is effective in slowing the progression toward kidney failure. Initiation of treatment for cardiovascular risk factors at earlier stages of chronic kidney disease should be effective in reducing cardiovascular disease events both before and after the onset of kidney failure.

At Hopkins GIM, our faculty are investigating several different aspects of the CKD epidemic, including: (1) genetics of CKD; (2) natural history of CKD and transition to renal failure; (3) screening for CKD in the general population; (4) optimal treatment to prevent progression; (5) optimal regime once renal replacement therapy is required; and (6) epidemiology and prevention of vascular complications in end-stage renal disease.

Information about the faculty working in this research area and their projects is provided below.

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Raquel Charles Greer, MD, MHS

Assistant Professor of Medicine

Research Interests: Quality of primary care for patients with CKD, patient education interventions to improve clinical outcomes and address race disparities in CKD care

To see publications abstracts: PUBMED

Each bimonthly issue of Advances in Chronic Kidney Disease presents focused review articles devoted to a single topic of current importance in clinical nephrology and related fields. The in-depth scholarly review articles explore the care and management of persons with early kidney disease and kidney failure, as well as those at risk for kidney disease. Emphasis is on articles related to the early identification of kidney disease; prevention or delay in progression of kidney disease; the multidisciplinary case management of patients with chronic kidney disease or kidney failure, organ effects of kidney disease; epidemiology and outcomes research in chronic kidney disease; benefits and complications of the primary treatment methods, dialysis and transplantation; technical aspects of the delivery of uremia therapy; care of the critically ill patient with kidney failure in the intensive care setting; new therapies for kidney failure; and health care research in chronic kidney disease. The full spectrum of basic science through clinical care is covered in these reviews. Clinical care issues stress the multidisciplinary team approach to the care of kidney patients. Topics covered will be of interest to practicing nephrologists (pediatric and adult), nephrology fellows (pediatric and adult), nurses, technicians, dietitians, and social workers caring for patients with kidney disease.

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